Search on: NSC 529592 
Descriptors Found: 1
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Descriptor English:   Aflatoxin B1 
Descriptor Spanish:   Aflatoxina B1 
Descriptor Portuguese:   Aflatoxina B1 
Synonyms English:   Aflatoxin B
Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer
Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled
Aflatoxin B1, cis(+,-)-Isomer
HSDB 3453
HSDB-3453
HSDB3453
NSC 529592
NSC-529592
NSC529592  
Tree Number:   D03.383.663.283.119.075
D03.633.100.150.119.075
D23.946.587.142.075
Definition English:   A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1. 
Indexing Annotation English:   /antag permitted but consider also ANTITOXINS
Pharmacological Action:   Poisons
 
History Note English:   92; was AFLATOXIN B1 (NM) 1980-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   30277 
Unique Identifier:   D016604 

Occurrence in VHL:
 

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